Thiazoline derivatives
US5478945A · kind A · utility
4Cited by
1References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 11, 1995 |
| Grant date | Dec 26, 1995 |
| Priority date | — |
| Expiry date | Jan 11, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/56
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A thiazoline derivative represented by the formula: ##STR1## [wherein R.sup.1 is cyano, carbamoyl, thiocarbamoyl, morpholinothiocarbonyl, alkylthioimidoyl, amidino, substituted amidino or imidazolin-2-yl, R.sup.2 is alkyl or aralkyl, R.sup.3 is hydrogen or alkyl, R.sup.4 is hydroxyl, alkoxy, substituted alkoxy or amino, l is an integer of 1 to 5] and salts thereof have fibrinogen receptor antagonism and cell adhesion factor antagonism, and are useful as therapeutic agents for ischemic diseases and atherosclerosis diseases, and metastasis inhibitory agents of tumors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.