Guanidino compounds as regulators of nitric oxide synthase
US5478946A · kind A · utility
10Cited by
2References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 30, 1993 |
| Grant date | Dec 26, 1995 |
| Priority date | — |
| Expiry date | Nov 30, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C281/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formula: ##STR1## useful as regulators of nitric oxide synthase that indirectly modulate cyclic guanosine monophosphate (cGMP), pharmaceutical compositions thereof, for treating disorders of vascular smooth muscles, macrophages, neurons, platelets, bronchial smooth muscles, optic muscles and gastrointestinal smooth muscles, sickle cell anemia and diabetes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.