3-hydroxypyridin-4-one derivatives as chelating agents
US5480894A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 7, 1994 |
| Grant date | Jan 2, 1996 |
| Priority date | — |
| Expiry date | Mar 7, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P39/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
3-Hydroxypyridin-4-ones of formula (I) ##STR1## in which R.sub.1 is a methyl, ethyl, 2-(.alpha.-methylpropionyloxy)ethyl or 2-pivoloyloxyethyl group and R.sub.2, R.sub.3 and R.sub.4 are each separately selected from hydrogen and methyl, ethyl, 2-(.alpha.-methylpropionyloxy)ethyl and 2-pivaloyloxyethyl groups with the provisos that (a) one only of R.sub.1 to R.sub.4 is either a 2-(.alpha.-methylpropionyloxy)ethyl group or a 2-pivaloyloxyethyl group, (b) at least one of R.sub.2 and R.sub.3 is other than hydrogen and (c) the total number of carbon atoms in R.sub.1 to R.sub.4 is no more than eleven, and physiologically acceptable salts thereof are of use in therapy, particularly in the treatment of conditions in which there is a toxic concentration of a metal, for example iron, in the body.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.