Peralkylated oligopeptide mixtures
US5480971A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 9, 1994 |
| Grant date | Jan 2, 1996 |
| Priority date | — |
| Expiry date | Jun 9, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/18
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Linear C.sub.1 -C.sub.7 -alkyl peralkylated oligopeptide sets of molecules are specific peralkylated oligopeptides, disclosed, as are their methods of synthesis and use in acceptor binding assays. Each molecule or chain of a set contains the same number of two to about ten substituted C.sub.1 -C.sub.7 -alkyl peralkylated amino acid residues, and the member chains of a set are present in equimolar amounts. The chains of a set contain one or more predetermined peralkylated amino acid residues at one or more predetermined positions of the peralkylated oligopeptide chain. The set contains equimolar amounts of at least six different peralkylated amino acid residues at one or more of the same predetermined positions of the peralkylated oligopeptide chain. Libraries of such sets, processes for their use and solid support-linked peralkylated sets are also contemplated, as are specific permethylated oligopeptides such as those having 5-8 phenylalanine residues that have antimicrobial properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.