Patent · US Expired

Bicyclopolyazamacrocyclocarboxylic acid complexes for use as contrast agents

US5480990A · kind A · utility

36Cited by
19References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 22, 1993
Grant dateJan 2, 1996
Priority date
Expiry dateDec 22, 2013

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K2123/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Complexes of bicyclopolyazamacrocyclocarboxylic acid with Gd, Mn or Fe ions are disclosed. The complexes can be covalently attached to a biologically active molecule, e.g. an antibody or antibody fragment, to form conjugates. The complexes and conjugates are useful as contrast agents for diagnostic purposes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.