Dual inhibitors of NO synthase and cyclooxygenase, therapeutical compositions containing them
US5480999A · kind A · utility
10Cited by
1References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 23, 1992 |
| Grant date | Jan 2, 1996 |
| Priority date | — |
| Expiry date | Dec 23, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/28
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to compounds of the general formula AB, which may be a salt or an amide, wherein: A represents a cyclooxygenase inhibitor having an accessible acidic function and B represents the L-form of arginine analogues of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 represent various substituents, process for the preparation of such compounds and pharmaceutical composition thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.