Patent · US Expired

Use of aryl- and heteroaryl piperazinyl carboxamides in the treatment of various central nervous system disorders

US5482940A · kind A · utility

6Cited by
10References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 15, 1993
Grant dateJan 9, 1996
Priority date
Expiry dateApr 15, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D295/13
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

There are disclosed the use of the compounds of the formula (I) ##STR1## wherein R.sup.1 is 1-adamantyl, 3-methyl-1-adamantyl, 3-noradamantyl, unsubstituted or substituted-2-indolyl, 3-indolyl, 2-benzofuranyl or 3-benzofuranyl wherein the substituents are selected from lower alkyl, lower alkoxy and halo; R.sup.2 is unsubstituted or substituted phenyl, benzyl, or pyrimidinyl wherein the substituents are selected from lower alkyl, lower alkoxy, trifluoromethyl and halo; R.sup.3 is H or lower alkyl of 1 to 3 carbon atoms; n is the integer 0 or 1; and m is the integer from 2 to 5 and the pharmaceutically acceptable salts thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.