Method for producing aclacinomycins A, B, Y using Strepomyces lavendofoliae DKRS
US5484712A · kind A · utility
0Cited by
7References
6Claims
0Family size
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Key dates
| Filing date | Jan 6, 1995 |
| Grant date | Jan 16, 1996 |
| Priority date | — |
| Expiry date | Jan 6, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/886
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed herein are a novel strain of Streptomyces and a method for the production of aclacinomycins A, B, Y and aglycone thereof by cultivating the same. Streptomyces lavendofoliae DKRS(KCTC 0092BP) of the present invention is capable of producing aclacinomycins A, B, Y and aglycone with higher yield. Further, it is possible to selectively produce aclacinomycin A or Y by adjusting pH of the cultured broth of Streptomyces lavendofoliae DKRS to 4.4 or 4.6 with acetate buffer or hydrochloric acid, respectively.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.