Patent · US Expired

Parathion hydrolase analogs and methods for production and purification

US5484728A · kind A · utility

6Cited by
1References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 1, 1994
Grant dateJan 16, 1996
Priority date
Expiry dateNov 1, 2014

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/815
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention provides a novel gene encoding DNA sequence for the expression of parathion hydrolase and an analog thereof, and methods for preparing such compounds. In a particularly preferred embodiment, the present invention relates to a parathion hydrolase gene encoding sequence in which twenty-eight amino acids are deleted from the N-terminal amino acid sequence of parathion hydrolase. The novel gene encoding parathion hydrolase encoding sequence is useful for production of the mature or processed parathion hydrolase and a methionine (-1) analog thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.