Phthalocyanine photosensitizers for photodynamic therapy and methods for their use
US5484778A · kind A · utility
25Cited by
3References
35Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 2, 1993 |
| Grant date | Jan 16, 1996 |
| Priority date | — |
| Expiry date | Sep 2, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC09B47/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a series of novel phthalocyanine compositions (or compounds) suitable for use as photosensitizers for photodynamic therapy. Specifically, the invention relates to a series of new aluminum (Al) germanium (Ge), gallium (Ga), tin (Sn) and/or silicon (Si) phthalocyanines having substituted amine or quaternary ammonium axial ligands attached to the central metal, and the use of these new phthalocyanine compositions for the treatment of cancer through photosensitization. Moreover, the present invention is directed to the methods of preparing these compositions for use in photodynamic therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.