Macromolecular microparticles and method of production
US5484894A · kind A · utility
6Cited by
5References
18Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 4, 1994 |
| Grant date | Jan 16, 1996 |
| Priority date | — |
| Expiry date | Mar 4, 2014 |
Classification
- Technology area (CPC —)General
Abstract
A macromolecular microparticle composition formed by dehydrating an aqueous macromolecule solution and crosslinking the dehydrated macromolecules with a crosslinking agent while in a liquid phase or with heat. Preferably, the dehydrating agent is a polymer mixture of polyvinylpyrrolidone and polyethylene glycol, the crosslinking reagent is glutaraldehyde, and the macromolecule is a protein, most preferably an immunoglobulin. Methods of use for research, diagnostics and therapeutics are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.