Human mesenchymal stem cells
US5486359A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 8, 1994 |
| Grant date | Jan 23, 1996 |
| Priority date | — |
| Expiry date | Feb 8, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/18
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Isolated human mesenchymal stem cells which can differentiate into more than one tissue type (e.g. bone, cartilage, muscle or marrow stroma), a method for isolating, purifying, and culturally expanding human mesenchymal stem cells (i.e. "mesenchymal stem cells" or "hMSCs"), and characterization of and uses, particularly research reagent, diagnostic and therapeutic uses for such cells. The stem cells can be culture expanded without differentiating. Monoclonal antibodies specific for human mesenchymal stem cells and the monoclonal hybridoma cell lines (ATCC nos. 10743-10745) that synthesize and secrete these monospecific antibodies, and uses of the monoclonal antibodies for diagnostic and/or therapeutic purposes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.