Calcium hydrogen phosphate, a method for preparing it, and an excipient utilizing it
US5486365A · kind A · utility
39Cited by
3References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 8, 1994 |
| Grant date | Jan 23, 1996 |
| Priority date | — |
| Expiry date | Jul 8, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC01B25/322
- WIPO fieldMaterials, metallurgy
- WIPO sectorChemistry
Abstract
The object of the present invention is to prepare a calcium hydrogen phosphate that has excellent binding properties, a large oil adsorption capacity and a specific surface area, and is therefore suitable as an excipient. A scale-like calcium hydrogen phosphate is prepared by reacting phosphoric acid with an alkaline calcium compound such as quick lime, in the presence of a multivalent organic acid with coordinating ability, such as citric acid, to obtain a columnar calcium hydrogen phosphate, and then hydrothermally treating the obtained columnar calcium hydrogen phosphate at a temperature of 60.degree. C. or higher.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.