Patent · US Expired

Method for increasing plasmid yield

US5487986A · kind A · utility

4Cited by
6References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 10, 1994
Grant dateJan 30, 1996
Priority date
Expiry dateMar 10, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N15/69
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

This invention relates to an aqueous medium formulation which is capable of allowing the growth of a plasmid-producing host cell to a density greater than 30 at a reading of 600 nm and, in addition, enhancing plasmid production beyond that which would be expected at the cell densities achieved. The medium of the present invention comprises a carbon source in the concentration range of about 20 to about 40 grams per liter of the water component of the medium.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.