Granular pharmaceutical formulations
US5489439A · kind A · utility
43Cited by
4References
18Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 19, 1993 |
| Grant date | Feb 6, 1996 |
| Priority date | — |
| Expiry date | Oct 19, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/2095
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A process for the preparation of a granule comprising a pharmaceutical which process comprises contacting a particulate, spray-dried substrate and a particulate pharmaceutical to obtain a particle comprising a substrate core carrying an adsorbed pharmaceutical and contacting the particle with a particulate pharmaceutical and a melted or thermally softened pharmaceutically acceptable excipient which is solid at room temperature to obtain, after cooling to solidify or harden the excipient, a granule comprising a spray-dried substrate core carrying pharmaceutically acceptable excipient and pharmaceutical.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.