Therapy and diagnosis of conditions related to telomere length and/or telomerase activity
US5489508A · kind A · utility
142Cited by
1References
11Claims
0Family size
Assignee
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Key dates
| Filing date | Mar 24, 1993 |
| Grant date | Feb 6, 1996 |
| Priority date | — |
| Expiry date | Mar 24, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/115831
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Method and compositions are provided for the determination of telomere length and telomerase activity, as well as the ability to inhibit telomerase activity in the treatment of proliferative diseases. Particularly, primers are elongated under conditions which minimize interference from other genomic sequences, so as to obtain accurate determinations of telomeric length or telomerase activity. In addition, compositions are provided for intracellular inhibition of telomerase activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.