Specific gene probes and processes for the diagnostic investigation of Candida albicans

US5489513A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Wolfgang Springer · Wuppertal, DE
• Manfred Plempel · Haan, DE
• Antonius Lobberding · Wuppertal, DE

Key dates

• Filing date: Oct 28, 1993
• Grant date: Feb 6, 1996
• Expiry date: Oct 28, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q1/6895
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Polynucleotide and oligonucleotide probes are described for the diagnostic investigation of mycoses which are caused by Candida albicans. These gene probes are complementary to parts of the genome of C. albicans and are suitable for identifying C. albicans nucleic acids in any sample material, even that which has been amplified. They do not hybridise with nucleic acids from other fungi, bacteria, animals or plants. Processes are described for the diagnosis of C. albicans in clinical samples as well.