Catalytic asymmetric reduction of enamines
US5489682A · kind A · utility
4Cited by
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8Claims
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Key dates
| Filing date | Feb 10, 1994 |
| Grant date | Feb 6, 1996 |
| Priority date | — |
| Expiry date | Feb 10, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A catalytic asymmetric reduction process, which, by hydrogenating enamines, yields a corresponding amine having a high level of enantiomeric purity is disclosed. The reduction process utilizes a chiral metal catalyst that includes a metal or metal complex that is selected from groups 3, 4, 5, or 6, lanthanides and actinides. Moreover, the process uses hydrogen as the stoichiometric reducing agent and may be carried out at pressures ranging from about 0.5 to 200 atmospheres.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.