Covalent bonding of active agents to skin, hair or nails

US5490980A · kind A · utility

Assignee

• Chesebrough-Pond's USA, division of Conopco, Inc. · US

Inventors

• Norman Richardson · Manchester, GB
• Kurt Schilling · Schwetzingen, DE
• David Joseph Pocalyko · Wayne, US
• Peter Lawrence Bailey · Bebington, GB

Key dates

• Filing date: Sep 28, 1994
• Grant date: Feb 13, 1996
• Expiry date: Sep 28, 2014

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61Q19/007
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Transglutaminase crosslinks proteins by catalyzing the formation of isopeptide bonds between lysine and glutamine residues. Transglutaminase may be used to crosslink beneficial actives containing an amine moiety to glutamine residues in skin, hair or nails. A variety of beneficial actives, e.g., sunscreens, antimicrobial compounds, skin conditioning agents, hair conditioning agents, anti-inflammatory compounds, antioxidants, coloring agents, perfumes, insect repellants, can thus be delivered to human skin, hair, or nails.