Direct label transaminated DNA probe compositions for chromosome identification and methods for their manufacture
US5491224A · kind A · utility
105Cited by
8References
16Claims
0Family size
Inventors
Key dates
| Filing date | Apr 4, 1994 |
| Grant date | Feb 13, 1996 |
| Priority date | — |
| Expiry date | Apr 4, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/81
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Direct label probe compositions which stain DNA of a preselected single chromosome or region of a chromosome of a multi-chromosomal genome are provided that comprise mixed DNA segments which are covalently bound to fluorophore groups through linking groups. The mixed DNA segments are derived from the DNA present in the preselected chromosome or chromosome region. These probe compositions can be used concurrently or sequentially with other probe compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.