Process for purifying vinylically unsaturated compounds prepared using a palladium-complex catalyst
US5491250A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 23, 1995 |
| Grant date | Feb 13, 1996 |
| Priority date | — |
| Expiry date | Mar 23, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/0838
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A crude vinylically unsaturated product formed from a palladium-complex-catalyzed reaction of a reactant halide selected from the group consisting of aryl, allyl, vinyl, and benzyl halides, and a reactant olefin having a vinylic hydrogen, wherein the reaction is carried out in the presence of a hydrogen halide acceptor, is purified by first contacting the crude product with a base that is stronger than the hydrogen halide acceptor, then heating the stronger base-contacted product. The purified product shows a marked reduction in concentration bromine and palladium impurities. The product can then be further purified by such methods as chromatography, crystallization, or distillation to achieve a product that is more suitable for applications where very low levels of inorganic impurities are required.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.