Patent · US Expired

Surface modified anticancer nanoparticles

US5494683A · kind A · utility

133Cited by
16References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 28, 1994
Grant dateFeb 27, 1996
Priority date
Expiry dateDec 28, 2014

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB82Y5/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Dispersible particles consisting essentially of a crystalline anticancer agent having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 1000 nm. Anticancer compositions comprising the particles exhibit reduced toxicity and/or enhanced efficacy, and can be administered by IV bolus injection.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.