Patent · US Expired

Piperidines and piperazines

US5495022A · kind A · utility

2Cited by

3References

15Claims

0Family size

Assignee

Merck Patent GmbH · DE

Inventors

Manfred Baumgarth
Inge Lues · Darmstadt, DE
Klaus-Otto Minck · Ober-Ramstadt, DE
Norbert Beier · Reinheim, DE

Key dates

Filing date	Jun 24, 1994
Grant date	Feb 27, 1996
Priority date	—
Expiry date	Jun 24, 2014

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D405/06
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Piperidine and piperazine derivatives of formula I ##STR1## wherein R.sup.1 and R.sup.2 are H or A, PA0 R.sup.3, R.sup.4 and R.sup.5 are each independently H, Hal, OH, OA, OAc, NO.sub.2, NH.sub.2, NHAc, NHSO.sub.2 A or CN, or PA0 R.sup.3 and R.sup.4 together are --O--(CH.sub.2).sub.m --O--, PA0 n is 0, 1 or 2 PA1 X is O or CH.sub.2, if n=0 or 2, or CH.sub.2, NH, NA or NAc, if n=1, PA0 Y is CH or N, PA0 m is 1 or 2, PA0 Hal is F, Cl, Br or I, PA0 A is C.sub.1-6 -alkyl, PA0 Ac is C.sub.1-8 -alkanoyl C.sub.1-10 -aralkanoyl or C.sub.7-11 -aroyl, and their physiologically acceptable salts show antiarrhythmic effects.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.