Plaque inhibition with antiplaque oral composition dispensed from container having polymeric material in contact and compatible with the composition

US5496540A · kind A · utility

Assignee

• Colgate-Palmolive Company · US

Inventors

• Abdul Gaffar · Somerville, US
• Richard Scott Robinson · Montgomery, US
• Jeffrey Miller · New York, US
• Chimpiramma Potini · East Brunswick Township, US
• Michael Collins · Hazlet, US
• Theresa G. Shackil · Vincentown, US

Key dates

• Filing date: Jan 10, 1994
• Grant date: Mar 5, 1996
• Expiry date: Jan 10, 2014

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61Q11/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque activity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition, but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula. The oral composition preferably contains a tooth hardening proportion of a source of fluoride ions, an anti-tartar proportion of a polyphosphate, a stabilizing proportion (in conjunction with the fluoride source) for the polyphosphate, of a polyvinyl methyl ether-maleic anhydride copolymer, and normal adjuvants for the oral preparation. A method for inhibiting developmen…