High molecular weight collagen-like protein polymers
US5496712A · kind A · utility
44Cited by
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21Claims
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Key dates
| Filing date | Nov 5, 1992 |
| Grant date | Mar 5, 1996 |
| Priority date | — |
| Expiry date | Nov 5, 2012 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG03C1/047
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Collagen-like polymers having repetitive triads are produced having reduced proline content, where glycine is the initial amino acid and the subsequent amino acids are varied, while retaining at least a minimum percentage of prolines. The resulting polymers have collagen-like properties, but are capable of being produced in unicellular microorganisms at high molecular weights and in high efficiency. The polymers while retaining collagen-like characteristics, include various novel sequences which impart new characteristics, finding wide use in photographic, medical, structural and fiber applications.
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