Method for producing non-neoplastic, three dimensional, mammalian tissue and cell aggregates under microgravity culture conditions and the products produced therefrom

US5496722A · kind A · utility

Assignee

• The United States of America as represented by the Administrator of the National Aeronautics and Space Administration · US

Inventors

• Thomas J. Goodwin · Friendswood, US
• David A. Wolf, Sr. · Houston, US
• Glenn F. Spaulding · Houston, US
• Tacey L. Prewett · Friendswood, US

Key dates

• Filing date: May 25, 1993
• Grant date: Mar 5, 1996
• Expiry date: May 25, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2531/00
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Normal mammalian tissue and the culturing process has been developed for the three groups of organ, structural and blood tissue. The cells are grown in vitro under microgravity culture conditions and form three dimensional cells aggregates with normal cell function. The microgravity culture conditions may be microgravity or simulated microgravity created in a horizontal rotating wall culture vessel.