Growth inhibitory factor from urogenital sinus
US5496800A · kind A · utility
1Cited by
11References
6Claims
0Family size
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Inventor
Key dates
| Filing date | Aug 11, 1992 |
| Grant date | Mar 5, 1996 |
| Priority date | — |
| Expiry date | Aug 11, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/828
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A process is provided for purifying Urogenital Sinus Derived Growth Inhibitory Factor (UGIF) from embryonic tissue which comprises chromatographing medium from cultures or culture-derived spheroids of embryonic tissue derived from the urogenital sinus by gel filtration chromatography. Further purification by reverse phase high pressure liquid chromatography is also demonstrated. The UGIF is obtained in 70-fold to 8000-fold purification over the conditioned medium. A UGIF composition of matter is also provided, as is a method for treating neoplasia with UGIF.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.