Disposable package for intrapulmonary delivery of aerosolized formulations
US5497763A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 14, 1993 |
| Grant date | Mar 12, 1996 |
| Priority date | — |
| Expiry date | Dec 14, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2230/40
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A disposable package is provided which makes it possible to hold and disperse therefrom liquid, flowable formulations including aqueous formulations (solutions or dispersions with particles less than 0.25 microns in diameter) of a pharmaceutically active drug. The formulation is packaged in individual dosage unit containers which containers are preferably interconnected. The package is designed to be integrated into a cassette which can be loaded into a dispersing device capable of individually opening dosage unit containers and aerosolizing the contents through a porous membrane, into a mouth piece on the cassette, for delivery to a patient. In addition to and alongside of each porous membrane, the package preferably includes one or more openings through which air is forced in order to aid in avoiding the accumulation of aerosolized particles. The package is configured so that the formulation is held in a container not positioned directly vertical to and below the porous membrane, thus making it necessary to channel formulation horizontally to the porous membrane and making it possible to include a vibrating mechanism directly below a chamber covered by the porous membrane. Releas…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.