Indole alkaloids useful as UV protective and anti-inflammatory agents

US5498405A · kind A · utility

Assignee

• The Regents of the University of California · US

Inventors

• William H. Gerwick · Corvallis, US
• Robert S. Jacobs · Lompoc, US
• Richard Castenholz · Eugene, US
• Ferran Garcia-Pichel · Bremen, DE
• Krista J. S. Grace · Goleta, US
• Philip J. Proteau · Murray, US
• James Christopher Rossi · Corvallis, US

Key dates

• Filing date: Jul 17, 1995
• Grant date: Mar 12, 1996
• Expiry date: Jul 17, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P29/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Indole alkaloid compounds having the formula ##STR1## where R and R' are H, an alkyl group having up to 5 carbon atoms or --CO--(CH.sub.2).sub.n --CH.sub.3 where n=0 to 16. The indole alkaloid compounds and their reduction products are useful as both UV protective and anti-inflammatory agents.