Solutions for the perfusion, preservation and reperfusion of organs
US5498427A · kind A · utility
74Cited by
2References
7Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 18, 1994 |
| Grant date | Mar 12, 1996 |
| Priority date | — |
| Expiry date | Aug 18, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/063
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Perfusion and preservation and/or reperfusion solutions for surgery and organ transplantation, including that of the heart, a feature of which solutions is the inclusion of at least one antioxidant compound, such as a trapping agent for free oxygen radicals, in particular glutathione in the reduced state or N-acetylcysteine, said solutions possessing a zero or greatly reduced partial pressure of oxygen which is maintained substantially at this value up to the time of use. The solution is preferably presented in flexible bags impermeable to oxygen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.