Composition for nasal administration of desmopressin
US5498598A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Apr 25, 1995 |
| Grant date | Mar 12, 1996 |
| Priority date | — |
| Expiry date | Apr 25, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P15/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An aqueous composition for spray nasal administration of a synthetic analog of vasopressin (desmopressin; actate containing between 2.5 and 7.5 .mu.g per 100 .mu.l. The composition may additionally contain an osmotic-pressure controlling agent, such as sodium chloride, a preservative, such as chlorobutanol or benzalkonium chloride, and a buffer stabilizing the pH between about 4 and 6. Buffers containing citrate and/or phosphate are preferred. Also disclosed is a sealed container filled with the composition, an assembly comprising the container and a spray pump, and the use of the composition, the container, and the assembly in the management of urinary disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.