Guanidinealkyl-1,1-bisphosphonic acid derivatives process for their preparation and their use

US5498617A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Christoph Naumann · Niedernhausen, DE
• Hans-Jochen Lang · Hofheim, DE
• Jurgen K. Sandow · Königstein, DE
• Anne-Marie Moura · Moura, FR

Key dates

• Filing date: Nov 23, 1994
• Grant date: Mar 12, 1996
• Expiry date: Nov 23, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/5728
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Guanidinealkyl-1,1-bisphosphonic acid derivatives, process for their preparation and their use Compounds of the tautomeric formula Ia, Ib or Ic, ##STR1## where R is a radical of the formula ##STR2## are effective compounds for the treatment and prophylaxis of degenerative bone disorders. They are used as pharmaceuticals.