Process for preparing imidazopyridine derivatives
US5498715A · kind A · utility
8Cited by
1References
15Claims
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Key dates
| Filing date | Nov 29, 1994 |
| Grant date | Mar 12, 1996 |
| Priority date | — |
| Expiry date | Nov 29, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for preparing imidazopyridine derivatives of the general formula: ##STR1## wherein R.sub.1 is hydrogen or an alkyl group, and R.sub.2, R.sub.3 and R.sub.4 are identical or different and are hydrogen, an alkyl group, a cycloalkyl group, an aryl group, an aralkyl group or a halogen atom. In this process, a 2-amino-3-nitropyridine is hydrogenated in the presence of a hydrogenation catalyst and the hydrogenation product is condensed with a carboxylic acid simultaneously present in the reaction mixture to give the end product. The imidazopyridine derivatives are intermediates for the preparation of angiotensin II antagonists.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.