Immediate release tablet cores of insoluble drugs having sustained-release coating
US5500227A · kind A · utility
322Cited by
5References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 23, 1993 |
| Grant date | Mar 19, 1996 |
| Priority date | — |
| Expiry date | Nov 23, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/2866
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A controlled release tablet for oral administration is disclosed which has a tablet core including an insoluble therapeutically active agent having an aqueous solubility of less than or equal to about 5 mg/ml in a sufficient amount to render a therapeutic effect. The core provides rapid release of said therapeutically active agent upon exposure to aqueous solutions. The tablet core is coated with a controlled release coating permitting sustained release of said therapeutically active agent when said coated tablet is exposed to aqueous solutions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.