Human osteoclast-derived cathepsin
US5501969A · kind A · utility
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39Claims
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Assignee
Inventors
Key dates
| Filing date | Mar 8, 1994 |
| Grant date | Mar 26, 1996 |
| Priority date | — |
| Expiry date | Mar 8, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a human osteoclast-derived cathepsin (Cathepsin O) polypeptide and DNA(RNA) encoding such cathepsin O polypeptides. Also provided is a procedure for producing such polypeptide by recombinant techniques. The present invention also discloses antibodies, antagonists and inhibitors of such polypeptide which may be used to prevent the action of such polypeptide and therefore may be used therapeutically to treat bone diseases such as osteoporosis and cancers, such as tumor metastases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.