N-terminus modified analogs of LHRH
US5502035A · kind A · utility
21Cited by
13References
8Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 27, 1994 |
| Grant date | Mar 26, 1996 |
| Priority date | — |
| Expiry date | Jul 27, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Decapaptide and undecapaptides substituted on the N-terminal nitrogen atom by acyl groups which include furo-2-yl, isonicotinyl, nicotinyl, 2-, 3-, and 4-quinolinecarbonyl, shikimyl, dihydroshikimyl, and tetrahydrofur-2-oyl are potent antagonists of LHRH and are useful for suppressing the levels of sex hormones in mammals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.