Patent · US Expired

Use of hydroxyethyl starch for improvement of microcirculation

US5502043A · kind A · utility

4Cited by

0References

4Claims

0Family size

Assignee

Fresenius AG · DE

Inventors

Burghard Weidler · Rosbach, DE
Klaus Sommermeyer · Rosbach, DE
Klaus Henning · Usingen, DE
Frank Bepperling · Bad Nauheim, DE

Key dates

Filing date	Mar 30, 1994
Grant date	Mar 26, 1996
Priority date	—
Expiry date	Mar 30, 2014

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC08L3/08
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The use of a hydroxyethyl starch specification with a molecular weight M.sub.W of 110,000 to 150,000, a substitution level MS of 0.38 to 0.5, a substitution level DS of 0.32 to 0.45, and a C.sub.2 /C.sub.6 ratio from 8 to 20 for improvement of microcirculation in a peripheral arterial circulation disorder, in particular in already existing peripheral arterial occlusive disease in Stage II according to Fontaine. This hydroxyethyl starch specification can be used in suitable concentrations, e.g., as 6 wt.-% or 10 wt.-% solution, whereby these solutions optionally contain conventional adjuvants and additives.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.