Mechanism based inhibitors of DNA methyltransferase
US5503975A · kind A · utility
11Cited by
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3Claims
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Key dates
| Filing date | Jun 22, 1992 |
| Grant date | Apr 2, 1996 |
| Priority date | — |
| Expiry date | Jun 22, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Novel synthetic oligomers of unique three-dimensional structure comprising homologous and heterologous blocks, some of which may self-associate are described. Also disclosed is a synthetic oligonucleotide that includes 5-fluorocytosine residues at positions corresponding to methylation sites of DNA-cytosine methyltransferase and a method for preparing such a molecule.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.