Method for identification of high affinity DNA ligands of HIV-1 reverse transcriptase
US5503978A · kind A · utility
146Cited by
3References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 6, 1994 |
| Grant date | Apr 2, 1996 |
| Priority date | — |
| Expiry date | May 6, 2014 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/976
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods are described for the identification and preparation of DNA ligands to the HIV-1 reverse transcriptase protein. The invention encompasses specific ssDNA ligands to HIV-1 reverse transcriptase identified by the SELEX method including ssDNA ligands that inhibit the activity of HIV-1 reverse transcriptase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.