Macrophage inflammatory protein-3 and -4
US5504003A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 8, 1994 |
| Grant date | Apr 2, 1996 |
| Priority date | — |
| Expiry date | Mar 8, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There is disclosed a human macrophage inflammatory protein-3 (MIP-3) and a human macrophage inflammatory protein-4 (MIP-4) polypeptides and DNA (RNA) encoding such polypeptides. There is also provided a procedure for producing such polypeptides by recombinant techniques and for producing antibodies against such polypeptides. In the invention there is also provided antagonist/inhibitors against such polypeptides which inhibit the functioning of such polypeptides. Another aspect of the invention provides a combination of the polypeptides of the present invention and a suitable pharmaceutical carrier for providing a therapeutically effective amount of the polypeptides for the treatment of various associated diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.