Calibration solutions useful for analysis of biological fluids and methods employing same
US5505828A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 2, 1995 |
| Grant date | Apr 9, 1996 |
| Priority date | — |
| Expiry date | Feb 2, 2015 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2496/80
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Novel calibration solutions are provided which are useful, for example, with sensor assemblies used for analysis of CO.sub.2, and optionally, for concurrent analysis of O.sub.2, especially in combination infusion fluid delivery/blood chemistry analysis systems which include a sensor assembly with each of the assembly electrodes mounted in an electrode cavity in the assembly. The analysis system used in the practice of the present invention typically includes provision for delivering infusion fluid and measuring blood chemistry during reinfusion of the physiological fluid at approximately the same flow rates. The invention calibration solutions are useful for calibrating an array of sensors capable of simultaneously measuring a number of blood chemistry parameters, including the partial pressures (tensions) of carbon dioxide and oxygen, pH (hydrogen ion), sodium, potassium, ionized calcium, ionized magnesium, chloride, glucose, lactate and hematocrit, in body fluids. More particularly, this invention relates to the use of an infusible intravenous solution to facilitate calibration on a regular basis for every individual sensor in a sensor assembly, which is in constant fluid communi…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.