.DELTA.5-androstenes useful for promoting weight maintenance or weight loss and treatment process
US5506223A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 24, 1994 |
| Grant date | Apr 9, 1996 |
| Priority date | — |
| Expiry date | Oct 24, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J1/0022
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for promoting weight control by treating a subject with a therapeutic amount of one of the .DELTA.5-androstenes listed below to stimulate weight control without affecting appetite or inducing the synthesis of sex hormones. .DELTA.5-Androstenes providing the desired biological activities include: PA0 .DELTA.5-Androstene-3.beta.,7.alpha.-diol-17-one (1) PA0 .DELTA.5-Androstene-3.beta.-ol-7,17-dione (2) PA0 .DELTA.5-Androstene-3.beta.,7.alpha.,17.beta.-triol (3) PA0 .DELTA.5-Androstene-3.beta.,17.beta.-diol-7-one (4) PA0 .DELTA.5-Androstene-3.beta.-acetoxy-7,16,17-trione (5) PA0 .DELTA.5-Androstene-3.beta.,16.alpha.-dihydroxy-7,17-dione (6) PA0 .DELTA.5-Androstene-3.beta.-propionoxy-16.beta.-acetoxy-7,17-dione (7) PA0 .DELTA.5-Androstene-3.beta.,7.alpha.,17.beta.-triol-16-one (8) PA0 .DELTA.5-Androstene-3.beta.,17.beta.-diol-7,16-dione (9) PA0 .DELTA.5-Androstene-3.beta.,16.alpha.,17.beta.-triol-7-one (10) and derivatives thereof wherein one or more of the hydroxyl or keto substituents is a group convertible thereto by hydrolysis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.