Patent · US Expired

Antibacterial penem compounds

US5506225A · kind A · utility

3Cited by
3References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 19, 1993
Grant dateApr 9, 1996
Priority date
Expiry dateFeb 19, 2013

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P31/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Antibiotic penem compounds are represented by the following formula: ##STR1## wherein R represents a physiological-hydrolyzable, ester-forming group. The physiologically hydrolyzable, ester-forming group useful in the penem compound of the present invention means a group which can be removed easily by in vivo hydrolysis, such as an acetyloxymethyl, 1-(acetyloxy)ethyl, pivaloyloxymethyl, 1-(ethoxycarbonyloxy)ethyl, 1-(isopropyloxycarbonyloxy)ethyl, 1-(cyclohexyloxycarbonyloxy)ethyl or 3-phthalidyl group. Antibiotic compositions for oral administration are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.