Arylsufonamido-substituted hydroxamic acids
US5506242A · kind A · utility
80Cited by
6References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 24, 1994 |
| Grant date | Apr 9, 1996 |
| Priority date | — |
| Expiry date | Jun 24, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a method of inhibiting metalloellastase activity, of inhibiting the degradation of elastin, or of treating macrophage metalloelastase dependent conditions in mammals which comprises administering to a mammal in need thereof an effective macrophage metalloelastase inhibiting amount of a compound of formula I ##STR1## wherein Ar, R, R.sub.1 and R.sub.2 have meanings as defined, or of a pharmaceutically acceptable prodrug derivative thereof, or of a pharmaceutically acceptable salt thereof, or of pharmaceutical compositions comprising a said compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.