Patent · US Expired

Proline derivatives possessing prolyl endopeptidase-inhibitory activity

US5506256A · kind A · utility

7Cited by
5References
4Claims
0Family size

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Key dates

Filing dateFeb 26, 1993
Grant dateApr 9, 1996
Priority date
Expiry dateFeb 26, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/06
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Novel proline derivatives of the following formula (I) ##STR1## wherein each symbol is as defined in the specification, which specifically inhibit prolyl endopeptidase activity and can be used for the prevention and/or treatment of dementia and amnesia as agents which act directly on the central symptoms of dementia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.