Compounds containing a fused bicycle ring and processes therefor
US5508272A · kind A · utility
172Cited by
27References
39Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 5, 1994 |
| Grant date | Apr 16, 1996 |
| Priority date | — |
| Expiry date | May 5, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the formula ##STR1## wherein X is O or S--(O).sub.t ; n is one or two; m is zero or one; Y is CH.sub.2, O, or S--(O).sub.t provided that Y is O or S--(O).sub.t only when m is one; and A is ##STR2## are dual inhibitors of NEP and ACE. Compounds wherein A is ##STR3## are selective ACE inhibitors. Also disclosed are methods of preparation and intermediates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.