Methods of inhibiting thrombin
US5508292A · kind A · utility
22Cited by
4References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 14, 1995 |
| Grant date | Apr 16, 1996 |
| Priority date | — |
| Expiry date | Apr 14, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of inhibiting thrombin and its attending diseases and conditions comprising administering to a human in need of treatment an effective amount of a compound having the formula ##STR1## wherein R.sup.1 and R.sup.3 are independently hydrogen, --CH.sub.3, ##STR2## wherein Ar is optionally substituted phenyl; R.sup.2 is selected from the group consisting of pyrrolidino, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.