LTB4 synthesis inhibitors
US5508309A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 1, 1994 |
| Grant date | Apr 16, 1996 |
| Priority date | — |
| Expiry date | Jul 1, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/081
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to a compound of the formula: ##STR1## or a pharmaceutically acceptable salt thereof wherein X is oxygen, sulfur, --CH.dbd.CH--, or --CH.dbd.N--; PA1 wherein R.sup.1 is --CO.sub.2 R.sup.2 or tetrazole; PA1 wherein R.sup.2 is hydrogen, alkyl of 1 to 6 carbons or a pharmaceutically acceptable cation; PA1 wherein R is an alkyl of from 1 to 20 carbons, --(CH.sub.2).sub.p CF.sub.3 or --(CH.sub.2).sub.q R.sup.3 wherein R.sup.3 is alkoxy, phenoxy or alkoxy substituted phenoxy wherein the alkoxy group has from 1 to 8 carbons; PA1 wherein p and q are integers from 0 to 20; PA1 wherein n is 0 or 1; and PA1 wherein m is 0, 1, 2, or 3.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.