Patent · US Expired

Diterpenes having immunomodulatory action

US5508390A · kind A · utility

0Cited by

6References

6Claims

0Family size

Assignee

Merck Patent GmbH · DE

Inventors

Hans-Eckart Radunz · Darmstadt, DE
Michael Wolf · Darmstadt, DE
Manfred Baumgarth
Willy Kinzy · Inzlingen, DE
Gerd-Albrecht Luckenbach · Darmstadt, DE

Key dates

Filing date	Feb 15, 1991
Grant date	Apr 16, 1996
Priority date	—
Expiry date	Feb 15, 2011

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P37/00
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Diterpenes of the formula I ##STR1## in which R.sup.1 is --CH.sub.2 --C(CH.sub.3).dbd.CH--R.sup.3 or --CH.sub.2 --CH(CH.sub.3)--CH.sub.2 --R.sup.3, PA1 R.sup.3 is --CH.sub.2 OH, --CHO, --COOH or --COOR.sup.4, PA1 R.sup.4 is alkyl having 1 to 5 C atoms, PA1 A is ##STR2## and R.sup.2 is H, pentoses, hexoses, di-/oligosaccharides or amino sugars, are suitable for production of medicaments having immunomodulatory action, in particular stimulating T-cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.