Derivatives of perhydroisoindole and preparation thereof
US5508433A · kind A · utility
2Cited by
2References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 17, 1993 |
| Grant date | Apr 16, 1996 |
| Priority date | — |
| Expiry date | Nov 17, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/44
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to derivatives of perhydroisoindol of formula: ##STR1## in which the radicals R are hydrogen atoms or together form a bond, the symbols R.sub.2 are phenyl radicals which can be substituted by a halogen atom or a methyl radical in position 2 or 3, R.sub.3 is a halogen atom or a hydroxy radical, R.sub.4 is H or halogen if R.sub.3 is halogen, in their isomer forms, or mixture thereof, and possibly also their salts when they exist, and preparation thereof. The derivatives of the invention are particularly interesting as P substance antagonist.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.